PREVALENCE OF DIABETIC NEPHROPATHY AMONGST TYPE 2 DIABETIC PATIENTS ATTENDING TERTIARY HOSPITAL OF HYDERABAD, SINDH, PAKISTAN

Authors

  • Noshaba Zaheer Khan Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan
  • Tahira Jabeen Ursani Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan
  • Jawaid Ahmed Khokhar Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan
  • Samina Malik Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan
  • Muhammad Junaid Khilji Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan
  • Shadab Kaka Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan
  • Khalid Hussain Dhiloo Department of Entomology, Faculty of Crop Protection, Sindh Agriculture University Tandojam, 70060, Pakistan
  • Sabina Shaikh Department of Zoology, University of Sindh, Jamshoro- 76080 Pakistan

DOI:

https://doi.org/10.34016/pjbt.2024.21.02.869

Keywords:

Prevalence, Diabetic, Nephropathy, Type 2 Diabetic, Patients, Tertiary Hospital, Hyderabad, Sindh, Pakistan

Abstract

Diabetic nephropathy (DN) is a common health problem; increasing with high proportion that results in significant reduction in life spawn of diabetic patients. This study was made in order to determine the prevalence of DN in patients having type 2 diabetes in major tertiary hospitals of Hyderabad and Adjoining areas. The progression of DN in Type 2 diabetic mellitus was gathered through pre-tested questionnaire from patients. During study period, 150 of DN patients were interviewed on the basis of their medical history including period of disease, blood sugar test, renal impairment, hypertension, cardiovascular and family background reports. While the measurement of albumin to creatinine ratio and uric acids in a random urine sample were evaluated with biochemical blood/urine test and immunological assays. It was found that out of 150 diabetes patients, 123 have DN and among them male and female ratio was 81: 42 respectively. According to the parameters, the diabetic mellitus were in both DN and non diabetic nephropathy (NDN) patients, as far as the circulating level of sugar level in both DN and NDN is concern it was noted that range of fasting blood sugar was high 232.86± 15.85 mg /dl as compared to the normal value 80-120. The level of blood glucose in the NDN it was 136,25 ± 10.85 around 100 mg/dl lesser than the values in DN patients. It was further observed that the smocking and hypertension played main role in the prevalence of the disorder.

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References

Diabetic nephropathy (DN) is a common health problem which has been increasing with high proportion that results in significant reduction in life spawn of diabetic patients. It has also been observed that 20-40% type -2 diabetic patients with micro albuminuria (MAU) develop nephropathy 10-15 years after having diabetes. This study was made in order to determine the prevalence of diabetic nephropathy in the patients among type 2 diabetes in major tertiary hospitals of Hyderabad. Prevalence of DN in Type 2 diabetic mellitus patients from Hyderabad and adjoining areas was observed and the risk factors associated with DN in tertiary hospitals, Diabetic OPDs of Hyderabad were ensured which involved in the progression of DN in Type 2 diabetic mellitus through pre-tested questionnaire of latest and already enrolled patients. During this period, 150 DN patients were interviewed on the basis of their medical history including period of disease, blood sugar test, renal impairment, hypertension, cardiovascular and family background reports. While the measurement of albumin to creatinine ratio and uric acids in a random urine sample were evaluated with biochemical blood/urine test and immunological assays. It was found that out of 150 diabetes patients, 123 have DN and among them male and female ratio was 81: 42 respectively. According to the parameters, the diabetic mellitus were in both DN and non diabetic nephropathy (NDN) patients, as far as the circulating level of sugar level in both DN and NDN is concern it was noted that range of fasting blood sugar was high 232.86± 15.85 mg /dl as compared to the normal value 80-120. The level of blood glucose in the NDN it was 136,25 ± 10.85 around 100 mg/dl lesser than the values in DN patients. It was further observed that the smocking and hypertension played main role in the prevalence of the disorder. Conclusion: It was concluded that DN in T2DM patients was 82% and its prevalence was more in rural population than that of urban population. This high prevalence is alarming and indicates an impending pandemic of cardiovascular and renal disease

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Published

2024-05-25

How to Cite

Khan, N. Z., Ursani, T. J., Khokhar, J. A., Malik, S., Khilji, M. J., Kaka, S., … Shaikh, S. (2024). PREVALENCE OF DIABETIC NEPHROPATHY AMONGST TYPE 2 DIABETIC PATIENTS ATTENDING TERTIARY HOSPITAL OF HYDERABAD, SINDH, PAKISTAN. Pakistan Journal of Biotechnology, 21(2), 332–338. https://doi.org/10.34016/pjbt.2024.21.02.869

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Research Articles