A CLINICAL MANIFESTATION OF HEPATITIS C AMONG THE POPULATION OF HYDERABAD, PAKISTAN

Mairaj Bibi; Asghar Ali; Uroosa Sahar; Abdul Sajid; Santosh Kumar; Zameer Ali Palh; Syed Habib Ahmed Naqvi; Shahla Karim Baloch

doi:10.34016/pjbt.2023.20.02.785

Authors

Mairaj Bibi Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan
Asghar Ali Department of Chemistry, Government College University Hyderabad, Hyderabad 71000, Pakistan
Uroosa Sahar Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan.
Abdul Sajid Department of Chemistry, Government College University Hyderabad, Hyderabad 71000, Pakistan
Santosh Kumar Institute of Biotechnology & Genetic Engineering, University of Sindh, Jamshoro, Pakistan.
Zameer Ali Palh Department of Fresh Water Biology & Fisheries, University of Sindh, Jamshoro, Pakistan
Syed Habib Ahmed Naqvi
Shahla Karim Baloch Department of Biotechnology, Sindh Agriculture University, Tandojam, Sindh, Pakistan

DOI:

https://doi.org/10.34016/pjbt.2023.20.02.785

Keywords:

Hepatitis C virus, HCV Screening, , Hematological, Biochemical

Abstract

Hepatitis C is a noteworthy public health issue around the globe, resulting in liver-related problems. Almost 80% of HCV patients suffer from chronic circumstances and are likely to have liver ailments. Approximately 6% population of Pakistan is infected with HCV. In this study of 510 samples were collected from May 2022 to September 2022 from Hyderabad and adjacent areas. 291 out of 510 samples were affected by HCV. The collected samples were screened based on ELISA using recombinant HCV antigens. Biochemical and hematological factors were performed on HCV-infected patients. RBC, Hemoglobin, WBC, MCV, MCHC, and PLT were observed normally in all age groups. But WBC and PLT are high in the 10-20 age groups. Hematocrit and MCH were decreased as compared to normal levels. Bilirubin, SGPT, and Alkaline phosphate were high in some age groups but normal in other age groups. Albumin was found normal in all patients. These parameters were correlated to each other to know the causes and prevention of HCV.

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