STUDY OF ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF ESCHERICHIA COLI ISOLATED FROM NOSOCOMIAL INFECTIONS IN HILLAH CITY, IRAQ

Abstract

Escherichia coli is a Gram-negative , rod-shaped organism it present as commensal in the gut of human’s alsoits
isolates from many different types of animals as well as this kind of bacteria presence in water provides, so it’s
considered as an index of stool contamination .in addition this organism can causes diseases in the alimentary tract
,urinary tract includes urethra, bladder, otitis media and respiratory system. The current study aims to identify of
antimicrobial agents use in the treatment E. coli that it’s acquired by nosocomial infections. The E. coli has been
isolated and then exposure to different classes of antibiotics by using Vitek2 technique method. The total number of
E. coli was isolated is 45. the findings have appeared so resistance to Ticarcillin with in 45 (100%), Piperacillin 45
(100%), Ceftazidime 42 (93.4%), Cefepime and Aztreonam 43 (95.6%). On the other hand the samples was showed
high sensitivity with Amikacin 44 (97.8%), Imipenem 43 (95.6%), Meropenem 43 (95.6% ) and Gentamicin 37
(82.2%) , while of Piperacillin\Tazobactam 12 (26.7 %) and Tobramycin 7 (15.5%) has intermediate susceptibility to
antibiotics study .finally found the high frequency of resistance to Ticarcillin, Piperacillin,Ceftazidime,Cefeoime and
Aztreonam was seen among E. coli isolates. As a result they were not recommended the last drugs used for treatment
of E. coli infections as optimal therapy. Keywords : E. coli, Antimicrobial susceptibility, Nosocomial infections,
Vitek2 technique.