INTERACTION BETWEEN GROUP OF VITAMINS AND NANO DRUGS TO BRAINSTEM GLIOMA PROTEIN AND REDESIGNING THE CHEMICAL STRUCTURE

Abstract

Brainstem Gliomas are amongst the most subtle and deadliest disease in the field of cancer. It provides treatments include surgery, clinical approach, radiotherapy, and chemotherapy. Blood Brain Barrier (BBB) is very important part allows to circulate blood from brain to body parts. Provides difficulty in delivering nano-molecules efficiently into the brain and offers the medical side effects depends upon characteristics of drugs even that can be used to indicate the effectiveness of drugs in similar tumors. This challenge is to identify how efficiently applied drugs works in central nervous system. Bioinformatics approach in nanomedicine helps to find out the presence of drug molecules present in the body, where they are needed and where they will do the best. I.e. The delivery of drug in BBB focuses on increasing the bioavailability and curate cancer with updated redesigned Drug and protein interaction. So, it is all about to make efficient redesigned drug and view it in 3D. Our novel approach focuses on redesign and apply efficient ligand through BBB to the Mutated Brainstem Glioma sequence using CADD tools, comparing the efficiency with existing drugs and view it in systematic proposed 3D visualization tool.