SEROPREVALENCE OF RUBELLA, CYTOMEGALOVIRUS, HERPES, AND TOXOPLASMA GONDII IN RECURRENT ABORTED WOMEN IN BAGHDAD

Abstract

Recurrent Abortion (RA) in the general populations is common occurrence and often changes among different communities. This study was to determination the prevalence of Rubella, Cytomegalovirus, herpes, and Toxoplasma Gondii in Baghdad. Blood samples were collected from 210 women, 180 women with recurrent abortion (three or more abortions) in the first trimester and 30 women with a healthy pregnancy. Based on the clinical examination, and diagnostic laboratory findings of the rapid lateral immune chromatography assay (RLICA), and Enzyme-linked Immunosorbent assay (ELISA) test for TORCH examination measured serum levels of immunoglobulin (IgM and IgG) for Toxoplasmosis, cytomegalovirus, herpes, and rubella in aborted women. Depending on the result of ELISA test the patients were included women with recurrent abortion with sero-negative for TORCH test was 50 (27.8%), women with recurrent aborted with sero-positive for antitoxoplasma antibodies was 44 (24.5%), women with recurrent abortions suffering from infected with different causes such as cytomegalovirus, Rubella or Herpes ratio were 86 (47.7%) and women with a healthy pregnancy (normal third delivery or more and with no previously recognized miscarriage) was 30 (14.3%). Also the results pointed out that the seropositivity rate for CMV IgG, T. gondii IgG, Rubella IgG, and HSV IgG were higher in recurrent aborted women compared with CMV IgM, T. gondii IgM, Rubella IgM, and HSV IgM also in recurrent aborted women with highly significant difference (P<0.05). The results indicated that the efficacy of ELISA test was higher than rapid test in detecting of TORCH infections.