DOSE RESPONSE CURVE OF VARIOUS PLANT EXTRATS ON G+ve AND G-ve BACTERIAL ISOLATES

Abstract

The plant extracts are being significantly used in the treatment of various infectious diseases and have a greater impact in Unani medicines. This presentation explores the effects of test plant extracts of garlic and ginger juice and aqueous extracts of coriander and mint prepared in ethanol, methanol and acetaldehyde with the comparison of chloramphenicol and gentamycin antibiotics as control. Our observation revealed that, garlic juices at 25 µl concentrations are effective on S. aureus and E. coli whereas ginger showed maximum activity on Ps. aeruginosa, S. aureus whereas 20 µl concentration revealed antibacterial activity against E. coli respectively. The aqueous extracts of coriander and mint extractsprepared in ethanol has greater antimicrobial activity against Ps. aeruginosa and E. coli respectively as compared to Staphylococcus aureus and Streptococcus pyogenes. Spectroscopic observations showed antibacterial activity at 20 and 25 µl concentrations of mint and coriander0.121 and 0.118against E. coli, Pseudomonas aeruginosa and Pseudomonas aeruginosa, E. coli as compared to other strains at A600respectively.