ASSESSMENT OF TOTAL ANTIOXIDANT CAPACITY, INTERFERON- GAMMA AND INTERLEUKIN-6 IN IDIOPATHIC INFERTILE MEN

Abstract

Infertility is an overall issue that portrayed by multifactorial etiology including physiological, hereditary, irresistible, ecological factors and in addition autoimmunity. The goal of this investigation is the connection between the aggregate cell reinforcement limit level with specific cytokines; interleukin-6 (IL-6) and interferon gamma (IFN-γ) levels in fundamental liquid and blood of idiopathic Infertility and ripe male relationship with original liquid level. Blood and fundamental liquids were gathered from 70 guys with idiopathic Infertility and 20 males with demonstrated Infertility and were broke down for the level of TAC, IL-6, IFN-γ and original liquid quality. Fundamental TAC levels were p<0.05 and lower in those with idiopathic Infertility. A negative relationship was seen between sperm quality parameters and TAC levels in idiopathic Infertility men. A fascinating noteworthy height in serum and semen IFN-γ level was recognized in idiopathic Infertility men. Furthermore, altogether lifted serum and semen IL-6 level was likewise seen in a gathering of idiopathic Infertility men. Inconclusion, TAC level has a critical negative impact on sperm quality and subsequently adds to male Infertility. Novel cytokine miniaturized scale designs for patients with various sorts of Infertility may be proposed and hence, cytokine level estimation of IL-6 and IFN-γ in fundamental plasma is recommended to be incorporated into assessment of particular kinds of male Infertility.